ISSN 1662-4009 (online)

ey0016.8-10 | Clinical Trials - New Treatments | ESPEYB16

8.10. Treatment of Primary Aldosteronism with mTORC1 Inhibitors

B Trinh , M Hepprich , MJ Betz , T Burkard , C Cavelti-Weder , E Seelig , F Meienberg , DV Kratschmar , F Beuschlein , M Reincke , A Odermatt , MN Hall , MY Donath , MM Swierczynska

To read the full abstract: J Clin Endocrinol Metab. 2019; pii: jc.2019–00563.Primary aldosteronism (PA) is one of the most common causes of secondary hypertension, affecting ~6% of the adult general hypertensive population. Patients with PA are at increased risk of cerebrovascular and cardiovascular morbidity, renal abnormalities and metabolic syndrome. The activity of mTORC1 ...